|
Category:stabilizing agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white powder (est) |
| Assay: | 99.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 158.00 to 161.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 211.00 °C. @ 20.00 mm Hg
|
| Boiling Point: | 336.00 to 337.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 1.000000 mmHg @ 114.00 °C. |
| Vapor Density: | 4.8 ( Air = 1 ) |
| Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
|
| logP (o/w): | 2.260 |
| Soluble in: |
| | alcohol | | | water, 3808 mg/L @ 25 °C (est) | | | water, 2240 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor Type: nutty |
| Odor Strength:low |
| phenolic nutty |
| Odor Description:at 100.00 %. faint phenolic nutty |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| Aceto |
| Salicylic Acid
|
| American International Chemical, LLC. |
| Salicylic Acid from Wintergreen
|
| Aurochemicals |
| SALICYLIC ACID, Natural
|
| BOC Sciences |
| For experimental / research use only. |
| Salicylic Acid >98%
|
| Charkit Chemical |
| SALICYLIC ACID PHARMA/USP
|
| Charkit Chemical |
| SALICYLIC ACID TECH GRADE
|
| Charkit Chemical |
| SALICYLIC ACID USP
|
| EMD Millipore |
| For experimental / research use only. |
| Salicylic Acid
|
| Glentham Life Sciences |
| Salicylic acid, 99%
|
| Glentham Life Sciences |
| Salicylic acid, BP, Ph. Eur grade
|
| Global Essence |
| Salicylic Acid Natural
|
| Graham Chemical |
| Salicylic Acid
|
| Lipo Chemicals |
| Lipo® CD-SA
Odor: characteristic Use: Lipo® CD-SA is an aqueous solution of cyclodextrin-encapsulated salicylic acid. Salicylic acid is a topical keratolytic agent. This compound is used in many personal care products to enhance exfoliation of the surface stratum corneum and in acne treatment products. |
| Novacyl |
| Salicylic Acid Industrial Grade
|
| Novacyl |
| Salicylic Acid Manufactured in China
|
| Novacyl |
| Salicylic Acid Pharma Grade
|
| Novacyl |
| Salicylic Acid Purified Grade
|
| Novacyl |
| Salicylic Acid YSA
|
| Penta International |
| SALICYLIC ACID FOOD GRADE
|
| Penta International |
| SALICYLIC ACID NATURAL
|
| Penta International |
| SALICYLIC ACID USP CRYSTAL
|
| Penta International |
| SALICYLIC ACID USP POWDER
|
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Salicylic Acid ≥99%
|
| Sigma-Aldrich |
| Salicylic acid, ≥99%, FG
|
| Certified Food Grade Products |
| Silver Fern Chemical |
| Salicylic Acid
Odor: characteristic Use: Salicylic Acid is widely used in the cosmetics, personal care, and pharmaceutical industries. It is also used in the manufacture of aspirin and salicylates, resins, as a food preservative, and a fungicide. |
| TCI AMERICA |
| For experimental / research use only. |
| 2-Hydroxybenzoic Acid >99.5%(T)
|
| Ungerer & Company |
| Salicylic Acid Natural
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 22 - Harmful if swallowed.
R 36/38 - Irritating to skin and eyes.
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 891 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971
oral-mouse LD50 480 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 148, 1959.
oral-rabbit LD50 1300 mg/kg
Drugs in Japan Vol. 6, Pg. 291, 1982.
intraperitoneal-rat LD50 157 mg/kg
BEHAVIORAL: TREMOR
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(7-8), Pg. 31, 1992.
oral-mouse LD50 908 mg/kg
(Sado, 1973)
gavage-rat LD50 1050 mg/kg
(Hasegawa et al., 1989)
oral-cat LD50 400 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 148, 1959.
intraperitoneal-mouse LD50 300 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gendai no Rinsho. Vol. 3, Pg. 675, 1969.
intravenous-mouse LD50 184 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakugaku Zasshi. Journal of Pharmacy. Vol. 91, Pg. 550, 1971.
|
| Dermal Toxicity: |
skin-rabbit LD50 > 10000 mg/kg
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971
skin-rat LD50 > 2000 mg/kg
LIVER: OTHER CHANGES
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl
subcutaneous-mouse LD50 520 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS
CARDIAC: CHANGE IN RATE
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 38, Pg. 9, 1930.
subcutaneous-rabbit LDLo 6000 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1392, 1935.
skin-man TDLo 57 mg/kg
SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR
JAMA, Journal of the American Medical Association. Vol. 244, Pg. 660, 1980.
|
| Inhalation Toxicity: |
inhalation-rat LC50 > 900 mg/m3/1H
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971
inhalation-mammal (species unspecified) LC50 > 300 mg/m3
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(7-8), Pg. 31, 1992.
|
Safety in Use Information:
| Category: | | stabilizing agents |
| Recommendation for ortho-salicylic acid usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.024 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.03 (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 20 |
| Click here to view publication 20 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | - |
| beverages(nonalcoholic): | 5.00000 | 50.00000 |
| beverages(alcoholic): | 10.00000 | 100.00000 |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 10.00000 | 100.00000 |
| fruit ices: | 10.00000 | 100.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | 10.00000 | 100.00000 |
| meat products: | - | - |
| milk products: | 5.00000 | 50.00000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
|
European Food Safety Authority (EFSA) reference(s):
|
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23
View page or View pdf
|
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
|
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
|
Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
|
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf
|
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009)
View page or View pdf
|
Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
|
Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
|
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| NIOSH International Chemical Safety Cards:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):69-72-7 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :338 |
| National Institute of Allergy and Infectious Diseases:Data |
| SCCNFP:opinion |
| WGK Germany:1 |
| 2-hydroxybenzoic acid |
| Chemidplus:0000069727 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:69-72-7 |
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00805 |
| HMDB (The Human Metabolome Database): | HMDB01895 |
| FooDB: | FDB000882 |
| YMDB (Yeast Metabolome Database): | YMDB01322 |
| Export Tariff Code: | 2918.29.0800 |
| MedlinePlusSupp: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations:
salicylic acid formulations:
salicylic acid formulations:
preparation
dose (%)
product
manufacturer
fostex medicated cleansing bar
bristol-myers
salicylic acid cleansing bar
stiefel
cream
fostex medicated cleansing cream
bristol-myers
deep cleansing shower gel
glaxosmithkline
neutrogena clear pore treatment
neutrogena
propa ph peel-off acne mask
stri-dex clear gel maximum strength (with sd alcohol 9.3%)
blistex
hydrisalic (with sd alcohol 40b and propylene glycol)
pedinol
clear away gel (with alcohol 57.6% ww, ether 16.4% ww in flexible collodion)
schering-plough
compound w gel (with alcohol 57.6% and ether 16.42% in flexible collodion)
medtech
duoplant gel (with alcohol 67.5% in flexible collodion)
schering-plough
lotion
salac acne medication-cleanser (with benzyl alcohol)
bioglan
sebasorb (with attapulgite activated 10%)
summers
ointment
mg 217 sal-acid
triton
plaster
trans-ver-sal (with propylene glycol)
clear away
schering-plough
clear away plantar system
schering-plough
compound w one step pads
medtech
freezone pads
medtech
mediplast
beiersdorf
sal-acid
pedinol
pledgets (saturated with solution)
oxy balance daily cleansing pads (with sd alcohol 40b 40% and propylene glycol)
glaxosmithkline
stri-dex regular strength pads (with sd alcohol 28%)
blistex
stri-dex sensitive skin pads (with sd alcohol 28% and aloe)
blistex
noxzema 2-in-1 pads extra strength
procter & gamble
oxy balance maximum daily cleansing pads (with sd alcohol 40b 50% and propylene glycol)
glaxosmithkline
stayclear deep cleaning pads
boots
stri-dex pads maximum strength (with sd alcohol 40 44%)
blistex
stri-dex super scrub pads (with sd alcohol 54%)
blistex
shampoo
ionil plus (with sd alcohol 40 12%)
healthpoint
dhs sal shampoo
person & covey
neutrogena tsal maximum strength
neutrogena
solution
propa ph cleanser (with sd alcohol 40 25% and aloe)
propa ph normalsensitive astringent cleanser
sebucare lotion (with alcohol 61%)
bristol-myers squibb
multi-action astringent (with alcohol 38.8%)
glaxosmithkline
noxzema 2-in-1 astringent
procter & gamble
propa ph foaming face wash
propa ph maximum strength astringent cleanser
stayclear zone-controlled clearstick
boots
gordofilm (in flexible collodian)
gordon
clear away liquid (with 17% sd alcohol 32, ether 52% in flexible collodion)
schering-plough
compound w solution (with alcohol 21.2% and ether 63.5% in flexible collodion)
medtech
duofilm (with alcohol sd 32 17% and ether 52% in flexible collodion)
schering-plough
occlusal-hp (with isopropyl alcohol 63% in a polyacrylic vehicle)
bioglan
off-ezy wart remover (with alcohol 21% and ether 65% in flexible collodion)
salactic film (with isopropyl alcohol 2.7% in a flexible collodion)
pedinol
sal-plant gel (with isopropyl alcohol 2.5% in flexible collodion)
pedinol
wart-off (with alcohol 26.35% in flexible collodion)
pfizer
freezone (with alcohol 20.5% and ether 65.5% in flexible collodion)
medtech
|
Potential Blenders and core components note
Potential Uses:
| | antidandruff agents |
| | bacteriostatic |
| FR | castoreum |
| | fungicide |
| | hair conditioning |
| | keratolytics |
| | preservatives |
| | skin conditioning |
Occurrence (nature, food, other): note
Synonyms:
| | acidum salicylicum | | | amiperfect | | | amipreserve | | | benzoic acid, 2-hydroxy- | | | benzoic acid, o-hydroxy- | | 2- | carboxyphenol | | o- | carboxyphenol | | ortho- | carboxyphenol | | | compound W | | | domerine | | | duofilm | | | duoplant | | | fostex | | | freezone | | 2- | hydroxy-benzoic acid | | 2- | hydroxybenzene carboxylic acid | | 2- | hydroxybenzenecarboxylic acid | | 2- | hydroxybenzoic acid | | o- | hydroxybenzoic acid | | ortho- | hydroxybenzoic acid | | | phenol-2-carboxylic acid | | | retarder W | | 2- | salicylic acid | | o- | salicylic acid | | | salicylic acid crystalline/powder | | | salicylic acid natural | | | salicylic acid USP crystal | | | salicylic acid USP powder | | | saligel | | | salonil | | | sebucare | | | verrugon |
Articles:
| PubMed:Effects of salicylic acid and putrescine on storability, quality attributes and antioxidant activity of plum cv. 'Santa Rosa'. |
| J-Stage:Cellulase Applied to the Leaves of Sweet Pepper (Capsicum annuum L. var. grossum) Upregulates the Production of Salicylic and Azelaic Acids |
| PubMed:Effects of postharvest salicylic acid dipping on Alternaria rot and disease resistance of jujube fruit during storage. |
| PubMed:After-ripening induced transcriptional changes of hormonal genes in wheat seeds: the cases of brassinosteroids, ethylene, cytokinin and salicylic acid. |
| PubMed:Evaluation of the pharmacological properties of salicylic acid-derivative organoselenium: 2-hydroxy-5-selenocyanatobenzoic acid as an anti-inflammatory and antinociceptive compound. |
| PubMed:Toxicology of isoproturon to the food crop wheat as affected by salicylic acid. |
| PubMed:Eugenol enhances the resistance of tomato against tomato yellow leaf curl virus. |
| PubMed:Reciprocal crosstalk between jasmonate and salicylate defence-signalling pathways modulates plant volatile emission and herbivore host-selection behaviour. |
| PubMed:Application of Tb(4)O(7) nanoparticles for lasalocid and salicylate determination in food analysis. |
| PubMed:A systemic response of geophytes is demonstrated by patterns of protein expression and the accumulation of signal molecules in Zantedeschia aethiopica. |
| PubMed:Biotic elicitors effectively increase the glucosinolates content in Brassicaceae sprouts. |
| PubMed:Opening of Iris flowers is regulated by endogenous auxins. |
| PubMed:The effects of host defence elicitors on betacyanin accumulation in Amaranthus mangostanus seedlings. |
| PubMed:Two centrosymmetric dinuclear phenanthroline-copper(II) complexes with 3,5-dichloro-2-hydroxybenzoic acid and 5-chloro-2-hydroxybenzoic acid. |
| PubMed:Influence of elicitation with H?O? on phenolics content, antioxidant potential and nutritional quality of Lens culinaris sprouts. |
| PubMed:Novel interrelationship between salicylic acid, abscisic acid, and PIP2-specific phospholipase C in heat acclimation-induced thermotolerance in pea leaves. |
| PubMed:[Changes in H2O2 and salicylic acid contents as well as plasma membrane H+-ATPase activity and their relations in pea leaves during thermotolerance induction]. |
| PubMed:Phenolic Compounds from Halimodendron halodendron (Pall.) Voss and Their Antimicrobial and Antioxidant Activities. |
| PubMed:Hydrogen peroxide scavenging, antioxidant and anti-radical activity of some phenolic acids. |
| PubMed:Nematicidal activity of mint aqueous extracts against the root-knot nematode Meloidogyne incognita. |
| PubMed:Anti-inflammatory drugs selectively target sporangium development in Mucor. |
| PubMed:New CE-ESI-MS analytical method for the separation, identification and quantification of seven phenolic acids including three isomer compounds in virgin olive oil. |
| PubMed:Effect of chemical systemic acquired resistance elicitors on avenanthramide biosynthesis in oat (Avena sativa). |
| PubMed:Determination of the antioxidant capacity of active food packagings by in situ gas-phase hydroxyl radical generation and high-performance liquid chromatography-fluorescence detection. |
| PubMed:Effect of external stress on density and size of glandular trichomes in full-grown Artemisia annua, the source of anti-malarial artemisinin. |
| PubMed:Pleiotropic changes in Arabidopsis f5h and sct mutants revealed by large-scale gene expression and metabolite analysis. |
| PubMed:Aspirin inhibits secretagogue-stimulated and postprandial pancreatic exocrine secretion in conscious rats. |
| PubMed:Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle. |
| PubMed:Benzothiadiazole induces the accumulation of phenolics and improves resistance to powdery mildew in strawberries. |
| PubMed:Phenolic acid profiles in some small berries. |
| PubMed:Salicylate activity. 3. Structure relationship to systemic acquired resistance. |
| PubMed:Chemical marker for ALS-inhibitor herbicides: 2-aminobutyric acid proportional in sub-lethal applications. |
| PubMed:Development of a yeast bio-assay to screen anti-mitochondrial drugs. |
| PubMed:Inhibition of pancreatic lipase by phenolic acids--examination in vitro. |
| PubMed:Valine pathway is more crucial than phenyl propanoid pathway in regulating capsaicin biosynthesis in Capsicum frutescens mill. |
| PubMed:Metabolic profiling of root exudates of Arabidopsis thaliana. |
| PubMed:Adsorption and Chemical Modification of Phenols on a Silver Surface. |
| PubMed:Is there a role for dietary salicylates in health? |
|
a compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. it has bacteriostatic, fungicidal, and keratolytic actions. its salts, the salicylates, are used as analgesics. (from dorland's, 28th ed) Preservative, fungicide (superseded), prohibited in milk and wine
Salicylic acid is a colorless, crystalline organic carboxylic acid. Salicylic acid is toxic if ingested in large quantities, but in small quantities is used as a food preservative and antiseptic in toothpaste. It is also the key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts. The carboxyl group (COOH) can react with alcohols, forming several useful esters. The name derives from the latin word for the willow tree (Salix), from whose bark it can be obtained.; --Wikipedia; Salicylic acid treats acne by causing skin cells to slough off more readily, preventing pores from clogging up. This effect on skin cells also makes salicylic acid an active ingredient in several shampoos meant to treat dandruff. Use of straight salicylic solution may cause hyperpigmentation on unpretreated skin for those with darker skin types (Fitzpatrick phototypes IV, V, VI), as well as with the lack of use of a broad spectrum sunblock. Subsalicylate in combination with bismuth form the popular stomach relief aid known commonly as Pepto-Bismol. When combined the two key ingredients help control diarrhea, nausea, heartburn, and even gas. It is also very mildly anti-biotic.
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3D/inchi