EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium hydrosulfite
dithionous acid sodium salt (1:2)

Supplier Sponsors

Name:disodium dithionite
CAS Number: 7775-14-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-890-0
FDA UNII:2K5B8F6ES1
Nikkaji Web:J41.404B
MDL:MFCD00011640
Molecular Weight:174.10633856
Formula:Na2 O4 S2
NMR Predictor:Predict (works with chrome or firefox)
Category:food-contact surface of paper and paperboard
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.90 Sodium hydrosulfite (packaging) View - review
FDA Mainterm (SATF):7775-14-6 ; SODIUM HYDROSULFITE
FDA Regulation:
FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2800 Textiles and textile fibers.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.90 Substances migrating to food from paper and paperboard products.
 
Physical Properties:
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -2.756 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: reducing agents
viscosity controlling agents
 
Suppliers:
American Elements
Sodium Dithionite 99%
Odor: characteristic
Use: Sodium Dithionite is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
Covalent Chemical
Sodium Hydrosulfite
EMD Millipore
For experimental / research use only.
Sodium dithionite
sds
Kraft Chemical
Sodium Hydrosulfite
Krunal Group
Sodium Hydrosulphite
Shiva Chemicals and Pharmaceuticals
Sodium Hydrosulfite
Sigma-Aldrich
For experimental / research use only.
Sodium hydrosulfite technical grade, 85%
Wedor Corporation
SODIUM HYDROSULFITE
WholeChem
Sodium Hydrosulfite
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
food-contact surface of paper and paperboard
Recommendation for sodium hydrosulfite usage levels up to:
 not for fragrance use.
 
Recommendation for sodium hydrosulfite flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
EPA Substance Registry Services (TSCA):7775-14-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24489
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
disodium dithionite
Chemidplus:0007775146
EPA/NOAA CAMEO:hazardous materials
RTECS:JP2100000 for cas# 7775-14-6
 
References:
 disodium dithionite
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7775-14-6
Pubchem (cid):24489
Pubchem (sid):134990304
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
FooDB:FDB012995
Export Tariff Code:2831.10.0000
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•commercial sodium dithionite generally has a purity of about 88%. it contains about 3% of each of the following: sodium disulfite, sodium sulfite, sodium sulfate, and sodium carbonate. the latter stabilizes the na2s2o4. the total heavy metal content is generally < 20 ppm. the product from the zinc-dust process has a zinc content of up to 300 ppm. •grades: technical; reagent. dihydrate •blankit •burmol •hydros •hydrosulfite of commerce contains 85-90% na2s2o4. •k-brite •reductone •vatrolite •v-brite •v-brite b •virchem •virtex cc •virtex d •virtex l •virtex rd
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 reducing agents
 viscosity controlling agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 disodium dithionate
 disodium dithionite
 disodium hydrosulfite
 dithionous acid sodium salt (1:2)
 dithionous acid, disodium salt
 sodium dithionite
 sodium hydrosulphite
 sodium hyposulfite
 sodiumdithionite
 vatrolite
 

Articles:

PubMed:Effect of near-infrared irradiation on photoconversion of the water-soluble chlorophyll-binding protein of Chenopodium album.
PubMed:Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo.
PubMed:Effects of a hydrogen sulfide donor on spontaneous contractile activity of rat stomach and jejunum.
PubMed:Comparative study of bioactivity of collagen scaffolds coated with graphene oxide and reduced graphene oxide.
PubMed:Spectroscopic evidence for a 5-coordinate oxygenic ligated high spin ferric heme moiety in the Neisseria meningitidis hemoglobin binding receptor.
PubMed:Effects of hypoxia on progranulin expression in HT22 mouse hippocampal cells.
PubMed:Comparison of the protective effects of ferulic acid and its drug-containing plasma on primary cultured neonatal rat cardiomyocytes with hypoxia/reoxygenation injury.
PubMed:Using Chemical Release Surveillance Data to Evaluate the Public Health Impacts of Chlorine and Its Alternatives.
PubMed:Determination of benzo[a]pyrene-7,10-quinone in airborne particulates by using a chemiluminescence reaction of hydrogen peroxide and hydrosulfite.
PubMed:Enhancing effect of alcoholic solvent on hydrosulfite-hydrogen peroxide chemiluminescence system.
PubMed:Graphene oxide adsorption enhanced by in situ reduction with sodium hydrosulfite to remove acridine orange from aqueous solution.
PubMed:Analysis of hazardous organic residues from sodium hydrosulfite industry and utilization as raw materials in a novel solid lubricant production.
PubMed:Hydrogen peroxide-sodium hydrosulfite chemiluminescence system combined with high-performance liquid chromatography for determination of 1-hydroxypyrene in airborne particulates.
PubMed:[Determination of primary aromatic amines in crayons gas chromatography-mass spectrometry].
PubMed:The effect of chemical treatment on reduction of aflatoxins and ochratoxin A in black and white pepper during washing.
PubMed:Effect of reduced sulfur compounds on the fermentation of phosphoric acid pretreated sugarcane bagasse by ethanologenic Escherichia coli.
PubMed:[Synthesis of 2-amino-4, 5-diarylpyrimidines and their protective effects against oxygen-glucose deprivation in PC12 cells].
PubMed:A simple and efficient method to prepare graphene by reduction of graphite oxide with sodium hydrosulfite.
PubMed:Efficient identification and quantification of peptides containing nitrotyrosine by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry after derivatization.
PubMed:Validation of a spectrophotometric method for quantification of carboxyhemoglobin.
PubMed:Consideration of molecular arrangements in regio- and enantioselective reduction of an NAD model compound controlled by carbonyl oxygen orientation.
PubMed:Ph3As-catalyzed wittig-type olefination of aldehydes with diazoacetate in the presence of Na2S2O4.
PubMed:Rapid and sensitive HPLC method for the simultaneous determination of paraquat and diquat in human serum.
PubMed:Detection of 6-nitrotryptophan in proteins by Western blot analysis and its application for peroxynitrite-treated PC12 cells.
PubMed:Purification and some properties of sulfur reductase from the iron-oxidizing bacterium Thiobacillus ferrooxidans NASF-1.
PubMed:Identification of factors involved in recovery of heat-injured Salmonella Enteritidis.
PubMed:Microplate assay measurement of cytochrome p450-carbon monoxide complexes.
PubMed:O2-specific regulation of the ferrous heme-based sensor kinase FixL from Sinorhizobium meliloti and its aberrant inactivation in the ferric form.
PubMed:[Determination of anions in recycle sodium formate from sodium hydrosulfite industry with single column ion chromatography].
PubMed:8-nitroguanosine formation in viral pneumonia and its implication for pathogenesis.
PubMed:Effects of oxidizing adulterants on detection of 11-nor-delta9-THC-9-carboxylic acid in urine.
PubMed:A Redox-Sensitive Resin Linker for the Solid Phase Synthesis of C-Terminal Modified Peptides.
PubMed:Synthesis of 2-phenylbenzotriazole-type mutagens, PBTA-5 and PBTA-6, and their detection in river water from Japan.
PubMed:Purification and characterization of chorion peroxidase from Aedes aegypti eggs.
PubMed:Highly sensitive high-performance liquid chromatographic assay for methotrexate in the presence and absence of anti-methotrexate antibody fragments in rat and mouse plasma.
PubMed:Determination of organic anions in waste liquid of sodium hydrosulfite production by ion chromatography.
PubMed:Nitric oxide inhibits L-type Ca2+ current in glomus cells of the rabbit carotid body via a cGMP-independent mechanism.
PubMed:The kinetics of the reaction between NO and O2 as studied by a novel approach.
PubMed:Immobilization of N-carbamyl-D-amino acid amidohydrolase.
PubMed:Sodium hydrosulfite contractions of smooth muscle are calcium and myosin phosphorylation independent.
PubMed:Chemical synthesis of a novel aromatic amine mutagen isolated from water of the Nishitakase River in Kyoto and a possible route of its formation.
PubMed:Horseradish peroxidase-dependent oxidation of deuteroporphyrin IX into chlorins.
PubMed:Evidence for a novel heme adduct generated by the in vitro reaction of 2,4,6-trinitrotoluene with human hemoglobin using electrospray ionization mass spectrometry.
PubMed:[Syntheses and spectra of Mn(III)-chlorophyll-a and Mn(II)-chlorophyll-a].
PubMed:Monophosphoryl lipid A protects adult rat cardiac myocytes with induction of the 72-kD heat shock protein: a cellular model of pharmacologic preconditioning.
PubMed:Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite.
PubMed:Nucleotide-selective cleavage of duplex DNA by nitric oxide.
PubMed:Evidence for in vivo peroxynitrite production in human acute lung injury.
PubMed:In search of the real respiratory neurons: culture of medullary fetal cells sensitive to CO2 and low pH.
PubMed:Phosphorylation and Dephosphorylation of Guard-Cell Proteins from Vicia faba L. in Response to Light and Dark.
PubMed:Oxygen tension clamp around single neurons in vitro: a computerized method for studies on O2 deprivation.
PubMed:In search of the central respiratory neurons: II. Electrophysiologic studies of medullary fetal cells inherently sensitive to CO2 and low pH.
PubMed:Isolation of 6-mercaptopurine in human plasma by aluminum ion complexation for high-performance liquid chromatographic analysis.
PubMed:Induction of chalcone synthase in cell suspension cultures of carrot (Daucus carota L. spp. sativus) by ultraviolet light: evidence for two different forms of chalcone synthase.
PubMed:Endogenous ethylene production is a potential problem in the measurement of nitrogenase activity associated with excised corn and sorghum roots.
PubMed:Brain hemosiderin and superficial siderosis of the central nervous system.
PubMed:Characterization of the autofluorescence of rat liver plasma membranes.
PubMed:Hydrogen transfer by NADPH-dependent reductases in elongation of very-long-chain saturated and polyunsaturated fatty-acyl-CoA in swine cerebral microsomes.
PubMed:Cross-linking study of the quaternary fine structure of mitochondrial F1-ATPase.
PubMed:Spectrophotometric study on the oxidation of rutin by horseradish peroxidase and characteristics of the oxidized products.
PubMed:Simplified determination of carboxyhemoglobin.
PubMed:A simple spectrophotometry for determination of carboxyhemoglobin in blood.
PubMed:[Analysis of drug decomposition products. XXXVI. Spectrophotometric method of the simultaneous determination of vitamin K3 and its sodium hydrosulfite component].
PubMed:Evaluation of a chemical technique for determining the oxygen permeability of synthetic membranes.
PubMed:Induction of single strand scission in bacteriophage phi X174 replicative form I DNA by mitomycin C.
PubMed:Inactivation of bacteriophage phi X174 by mitomycin C in the presence of sodium hydrosulfite and cupric ions.
PubMed:Characterization of a flavoprotein iodotyrosine deiodinase from bovine thyroid. Flavin nucleotide binding and oxidation-reduction properties.
PubMed:Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood.
PubMed:Structure of nanaomycin E, a new nanaomycin.
PubMed:A new screening method for cystinuria. A simple and safe screening kit.
PubMed:Azo reduction of trypan blue to a known carcinogen by a cell-free extract of a human intestinal anaerobe.
PubMed:Folate analogues altered in the C9-N10 bridge region. 10-Oxafolic acid and 10-oxaaminopterin.
PubMed:Synthesis of N-10-methyl-4-thiofolic acid and related compounds.
PubMed:Metabolism of uronic acids in plant tissues: partial purification and properties of uronic Acid oxidase from citrus leaves.
PubMed:[Radiation-protective action of sodium hydrosulfite and metabisulfite].
PubMed:[Electrophoretic separation of tissue proteins on polyacrylamide gel, prepared by use of sodium hydrosulfite as initiator of polymerization].
PubMed:Oxidation of D-amino acids by a particulate enzyme from Pseudomonas aeruginosa.
PubMed:PURIFICATION OF THE SOLUBLE HEMOLYSINS OF LISTERIA MONOCYTOGENES.
PubMed:FORMATE--PYRUVATE EXCHANGE REACTION IN STREPTOCOCCUS FAECALIS. II. REACTION CONDITIONS FOR CELL EXTRACTS.
PubMed:Protection by sodium hydrosulfite against x-ray-induced mitotic inhibition in grasshopper neuroblast.
PubMed:Reduction of the x-ray sensitivity of escherichia coli by sodium hydrosulfite and certain other inorganic sulfur compounds.
PubMed:Reduction of x-ray sensitivity of Escherichia coli B/r by sulfhydryl compounds, alcohols, glycols, and sodium hydrosulfite.
PubMed:Interference With the Antibacterial Action of Streptomycin by Reducing Agents.
PubMed:STUDIES ON THE MECHANISM OF ANTIBACTERIAL ACTION OF 2-METHYL-1,4-NAPHTHOQUINONE.
PubMed:STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : I. PNEUMOCOCCUS HEMOTOXIN.
 
Notes:
Bleaching agent which may occur adventitiously in food, occurrence not well documented
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