EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

cetostearyl alcohol
1-octadecanol mixed with 1-hexadecanol

Supplier Sponsors

CAS Number: 67762-27-0Picture of molecule3D/inchi
Other(deleted CASRN):8005-44-5
ECHA EINECS - REACH Pre-Reg:267-008-6
FDA UNII:2DMT128M1S
Molecular Weight:512.94624000
Formula:C34 H72 O2
NMR Predictor:Predict (works with chrome or firefox)
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FDA Mainterm (IAUFC):67762-27-0 ; CETOSTEARYL ALCOHOL
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 334.00 to 335.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000009 mmHg @ 25.00 °C. (est)
Flash Point: 282.00 °F. TCC ( 138.70 °C. ) (est)
logP (o/w): 8.314 (est)
Soluble in:
 water, 0.1495 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. mild waxy
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: emollients
emulsifying agents
emulsion stabilisers
foam boosting agents
opacifying agents
surfactants
viscosity controlling agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Cetearyl alcohol 95%
Charkit Chemical
CETO STEARYL ALCOHOL
Croda
Cosmowax™ D
Odor: bland
Use: Nonionic emulsifying wax - an optimised combination of vegetable-derived emulsifiers and stabilisers.
Croda
Cosmowax™ J
Odor: bland
Use: Nonionic emulsifying wax - an optimised combination of vegetable-derived emulsifiers and stabilisers.
Croda
Crodacol™ CS50
Odor: bland
Use: Technically pure grade of vegetable-derived cetostearyl alcohol recommended for personal care applications. Impart dry waxy emollience to creams and lotions. Emulsion stabilisers and viscosity builders. Used to modify structure and feel of anhydrous salves and sticks.
Croda
Crodafos™ CES
Odor: bland
Use: Phosphate-based emulsifying and conditioning wax conferring excellent functionality to a wide range of personal care systems. Emulsifying wax and conditioning agent for wide ranging skin and hair care applications. Ideal for use in waterproof sun care where it has been proven to boost SPF and enhance resistance to wash-off. Can also be used in hair relaxer systems where it promotes rapid penetration of hydroxide ions and helps to prevent cuticle damage due to over processing.
Croda
Crodafos™ CS20A
Odor: bland
Use: High actives (50%) primary emulsifier designed to enhance viscosity control ? especially suited for pourable emulsions with high active loads (liquid foundations) or other medium to low viscosity products such as body sprays, milks and depilatories. An O/W emulsifier specifically designed for pourable emulsions with high active loads (e.g. liquid foundations) and other medium to low viscosity products e.g. sprayable emulsions. Naturally substantive to the skin and imparts conditioning benefits. Wide pH tolerance. Requires neutralisation which can be done in situ.
Croda
Crodex™ A
Odor: bland
Use: Anionic emulsifying wax conforming to the PhEur monograph.
Croda
Crodex™ N
Odor: bland
Use: Nonionic emulsifying wax - an optimised combination of vegetable-derived emulsifiers and stabilisers.
ECSA Chemicals
Cetearyl Alcohol
Company Profile
Galaxy Surfactants North America
SURFAWAX D
Odor: characteristic
Use: The product is a non-ionic, self emulsifying base with consistency giving properties. It is well suited for the preparation of cosmetic O/W lotions and creams.
Galaxy Surfactants North America
SURFOL O
Odor: characteristic
Use: Surfol O is an excellent emollient and viscosity building agent for lotions, creams, cream rinse conditioners, and numerous cosmetic preparations. Supplied as white flakes, Surfol O also serves as a co-emulsifier in formulated emulsion systems and is compatible with anionic, cationic and nonionic emulsifying surfactants.
HallStar
HALLSTAR® NCD-20
Odor: characteristic
Use: HallStar NCD-20 is a high quality, readily emulsifiable product. It consists of a defined proportion of Cetearyl Alcohol (common name Cetostearyl Alcohol or Cetyl Stearyl Alcohol) and Ceteareth-20. HallStar NCD-20 has broad pH stability and finds application as an oil-in-water (O/W) emulsion base. It may be used as the primary or secondary emulsifier in a wide variety of lotions, creams and pastes. Because it is not an ester and is nonionic, it can be used in systems far from neutral pH, such as hair relaxers, depilatories, creme lotion developers, and AHA skin care creams. HallStar NCD-20 is dispersible in hot water and is typically utilized at 1 to 2.5% when utilized as a co-emulsifier and at up to 10% of the finished product composition when it is the sole emulsifier.
Jarchem Industries
Jarcol™ I-167
Odor: characteristic
Use: A liquid product similar in properties to Isostearyl alcohol with a high amount of C17 alcohols.
Lipo Chemicals
Lipocol® SC-1618 Pastilles
Odor: characteristic
Use: Lipocol® SC-1618 is a blend of high quality cetyl and stearyl alcohols. It is a white waxy solid with a typically fatty odor. Lipocol® SC-1618 is widely used in the cosmetic industry in cream rinse applications and in emulsions where it acts as a viscosity builder and a co-emulsifier.
Lipo Chemicals
Lipocol® SC
Odor: characteristic
Use: Lipocol® SC is a blend of high quality cetyl and stearyl alcohols. It is a white waxy solid with a typically fatty odor. Lipocol® SC is widely used in the cosmetic industry in antiperspirant sticks and in cream rinse applications. It is also used in emulsions where it acts as a viscosity builder with a co-emulsifier.
Lipo Chemicals
Lipomulse® Luxe
Odor: characteristic
Use: Lipomulse® Luxe is a complete emulsifier system that forms liquid crystals for enhanced emulsion stability and shiny white emulsions. The unique blend of ingredients in Lipomulse® Luxe produce an elegant, soft feel that is long lasting and pleasant to the touch.
Lipo Chemicals
Lipowax® D
Odor: characteristic
Use: Lipowax® D is an emulsifier system that can be used in skin care creams & lotions, liquid foundations, hair color products, hair conditioners, peroxide creams and depilatories. Lipowax® D can be used with co-emulsifiers.
Lipo Chemicals
Lipowax® NI
Odor: characteristic
Use: Lipowax® NI forms fine-textured opaque emulsions. Lipowax® NI can be used as the sole emulsifier or in combination with ionic or other nonionic systems. It has good electrolyte tolerance.
Lipo Chemicals
Lipowax® P
Odor: characteristic
Use: Lipowax® P is an emulsifier system that disperses easily in warm water to form elegant opaque emulsions. Can be used with co-emulsifiers. Lipowax® P is used in hair conditioners and masks, skin care creams and lotions and body washes. It is especially suited for acidic pH preparations and also for hair relaxers having high pH.
Lipo Chemicals
Lipowax® R2
Odor: characteristic
Use: Lipowax® R2 is a complete emulsifying system which is a balanced blend of both lipophilic high molecular weight fatty alcohols and hydrophilic ethoxylated products. Easily dispersed in warm water, Lipowax® R2 forms white opaque emulsions of varied consistency depending on the concentration. Designed for use in hair relaxer systems, Lipowax® R2 also offers excellent performance in skin care formulations.
Mosselman
Cetostearylic Alcohol
Oleo Solutions
Alcohol C16-18 (30:70)
Odor: characteristic
Use: Cosmetics and Personal Care, Cleaning and Detergents, Industrial, Pharmaceutical and Veterinary
Oleo Solutions
Alcohol C16-18 (50:50)
Odor: characteristic
Use: Cosmetics and Personal Care, Cleaning and Detergents, Industrial, Pharmaceutical and Veterinary
OQEMA
LanCos EMCS
Penta International
CETOSTEARYL ALCOHOL
Strahl & Pitsch
Emulsifying Wax Pastilles SP-210P NF
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for cetostearyl alcohol usage levels up to:
 not for fragrance use.
 
Recommendation for cetostearyl alcohol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):67762-27-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :62238
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:nwg
hexadecan-1-ol; octadecan-1-ol
Chemidplus:0067762270
 
References:
 hexadecan-1-ol; octadecan-1-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:67762-27-0
Pubchem (cid):62238
Pubchem (sid):135020551
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 emollients
 emulsifying agents
 emulsion stabilisers
 opacifying agents
 viscosity controlling agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(C16-C18)alkyl alcohol
(C16-C18)-alkyl alcohol
 alkyl alcohols C16-18
 brookswax D
 cetax 50
 cetearyl alcohol
 cetyl-stearyl alcohol
 cetyl/stearyl alcohol
 cosmowax
 cosmowax D
 cosmowax J
 crodacol CS50
 crodacol CS90
 crodafos CES
 crodafos CS20A
 crodex A
 crodex N
 emulsifying wax pastilles SP-210P NF
 hallstar NCD-20
 hexadecan-1-ol; octadecan-1-ol
 jarcol I-167
 lanette O
 lipocol SC
 lipocol SC-1618 pastilles
 lipomulse luxe
 lipowax D
 lipowax NI
 lipowax P
 lipowax R2
1-octadecanol mixed with 1-hexadecanol
 

Articles:

PubMed:Drug-excipient compatibility studies in binary mixtures of avobenzone.
PubMed:Drug-excipient compatibility studies in binary mixtures of avobenzone.
PubMed:Development and characterization of controlled release polar lipid microparticles of candesartan cilexetil by solid dispersion.
PubMed:Reduced burning and stinging associated with topical application of lactic acid 10% with strontium versus ammonium lactate 12%.
PubMed:Sucrose stearate-enriched lipid matrix tablets of etodolac: modulation of drug release, diffusional modeling and structure elucidation studies.
PubMed:Contact dermatitis caused by fatty alcohols: may polyethoxylation of the fatty alcohols influence their sensitizing potential?
PubMed:Why aqueous cream should not be used in radiotherapy-induced skin reactions.
PubMed:Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide.
PubMed:Suitability of Gelucire 50/13 for controlled release formulation of salbutamol sulphate.
PubMed:Occupational allergic contact dermatitis from methyl aminolevulinate.
PubMed:A bilateral comparison study of pimecrolimus cream 1% and a topical medical device cream in the treatment of patients with atopic dermatitis.
PubMed:Formulation and in vitro evaluation of buoyant controlled release lercanidipine lipospheres.
PubMed:Natural surfactant-based topical vehicles for two model drugs: Influence of different lipophilic excipients on in vitro/in vivo skin performance.
PubMed:Development of extended release divalproex sodium tablets containing hypdrophobic and hydrophilic matrix.
PubMed:Topical vehicles based on natural surfactant/fatty alcohols mixed emulsifier: The influence of two polyols on the colloidal structure and in vitro/in vivo skin performance.
PubMed:Matrix embedded microspherules containing indomethacin as controlled drug delivery systems.
PubMed:Stabilizing effect of cetostearyl alcohol and glyceryl monostearate as co-emulsifiers on hydrocarbon-free O/W glyceride creams.
PubMed:In vitro skin permeation of sunscreen agents from O/W emulsions.
PubMed:In vitro controlled drug release from loaded microspheres--dose regulation through formulation.
PubMed:Empirical kinetic model of propafenone release from Hot Air Coating microparticles.
PubMed:Evaluation of lotion formulations on irritation using the modified forearm-controlled application test method.
PubMed:The physicochemical characterization and in vitro/in vivo evaluation of natural surfactants-based emulsions as vehicles for diclofenac diethylamine.
PubMed:An alkylpolyglucoside surfactant as a prospective pharmaceutical excipient for topical formulations: the influence of oil polarity on the colloidal structure and hydrocortisone in vitro/in vivo permeation.
PubMed:Effect of poloxamers on nifedipine microparticles prepared by Hot Air Coating technique.
PubMed:Vehicles based on a sugar surfactant: Colloidal structure and its impact on in vitro/in vivo hydrocortisone permeation.
PubMed:Stabilization of solid dispersions of nimodipine and polyethylene glycol 2000.
PubMed:Evaluation of hydrophobic materials as matrices for controlled-release drug delivery.
PubMed:Characterization of nifedipine microparticles prepared by hot air coating technique.
PubMed:Determination of anionactive tensides using cetylpyridinium tetrachlorozincate as titrant. Analytical methods in respect to environmental and economical concern, part 20.
PubMed:Final report on the amended safety assessment of diisopropyl dimer dilinoleate, dicetearyl dimer dilinoleate, diisostearyl dimer dilinoleate, dioctyl dimer dilinoleate, dioctyldodecyl dimer dilinoleate, and ditridecyl dimer dilinoleate.
PubMed:Allergic contact dermatitis from cetearyl isononanoate.
PubMed:The development of Cutina lipogels and gel microemulsion for topical administration of fluconazole.
PubMed:Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates.
PubMed:Radiolysis characterization of cetostearyl alcohol by gas chromatography-mass spectrometry.
PubMed:The British standard series of contact dermatitis allergens: validation in clinical practice and value for clinical governance.
PubMed:Allergic contact dermatitis from cetrimide and cetearyl alcohol in Burnol-plus cream.
PubMed:Synchrotron X-ray investigations into the lamellar gel phase formed in pharmaceutical creams prepared with cetrimide and fatty alcohols.
PubMed:An investigation into the supramolecular structure of ternary gel systems using oscillatory rheometry, microscopy, and low frequency dielectric spectroscopy.
PubMed:Effects of drug concentration in inner aqueous phase and additives in oleaginous phase on release and bioavailability of isoniazid from multiple emulsion.
PubMed:Contact sensitization in chronic venous insufficiency: modern wound dressings.
PubMed:Contact dermatitis from cetostearyl alcohol.
PubMed:Variation in cetostearyl alcohol and lecithin from different sources: evaluation by dielectric analysis.
PubMed:Multiple emulsion-based systems carrying insulin: development and characterization.
PubMed:High incidence of contact dermatitis in leg-ulcer patients--implications for management.
PubMed:Contact dermatitis from cetostearyl alcohol in hydrocortisone butyrate lipocream, and from lanolin.
PubMed:Emulsification by the phase inversion temperature method: the role of self-bodying agents and the influence of oil polarity.
PubMed:Contact dermatitis to Hirudoid cream.
PubMed:Water distribution in creams prepared using cetostearyl alcohol and cetrimide.
PubMed:An investigation of the structural changes occurring in a cetostearyl alcohol/cetrimide/water gel after prolonged low temperature (4 degrees C) storage.
PubMed:The effect of temperature on the conductivity of gels and emulsions prepared from cetrimide and cetostearyl alcohol.
PubMed:Reflectance measurements on gels and emulsions containing cetrimide and cetostearyl alcohol--a preliminary investigation.
PubMed:[Internal structure of oil-in-water emulsions stabilized with a cetostearyl alcohol].
PubMed:Allergy to cetylalcohol.
PubMed:[Contact allergy to cetylstearylalcohol (Lanette O) as a therapeutic problem in stasis dermatitis and leg ulcer].
PubMed:Lanette-O--another test substance for lower leg series.
PubMed:Proceedings: The structure of the continuous phases in creams stabilised by cetrimide and cetostearyl alcohol.
PubMed:The composition of cetostearyl alcohol.
PubMed:Rheology of systems containing cetrimide-cetostearyl alcohol: variation with temperature.
PubMed:The self-bodying action of the mixed emulsifier cetrimide-cetostearyl alcohol.
 
Notes:
component of creams, ointments, emulsifying agents. tsca definition 2008: this substance is identified by sda substance name: c16-c18 alkyl alcohol and sda reporting number: 19-060-00. consult sda substance identification procedure.
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